Papers to Appear


Cover image: The functional magnetic resonance imaging (fMRI) is one of the mainstream imaging modalities to study brain functional connectivity. In brain connectivity networks, the nodes represent brain regions and an edge indicates conditional dependence between the linked brain regions. Differential network analysis aims to identify the difference between the networks of two groups. It is of great interest to investigate how the network of connected brain regions alters from the disease group to the control group, which may shed light on the underlying pathogenic mechanism. The processed fMRI data have a spatial by temporal matrix structure, where the rows correspond to the brain regions while the columns correspond to the time points. The proposed matrix-variate differential network model is very flexible and the corresponding estimation procedure directly dig out the difference of spatial partial correlation matrices between two groups without attempting to estimate each partial correlation matrix separately. This comes from Figure 1 in the article authored by Jiadong Ji, Yong He, Lei Liu, and Lei Xie, and entitled "Brain connectivity alteration detection via matrix-variate differential network model."


Biometric Methodology


DISCUSSION PAPER

Causal mediation of semicompeting risks

Yen-Tsung Huang


Discussion

Kwun Chuen Gary Chan, Fei Gao, and Fan Xia


Discussion

Mats J. Stensrud, Jessica G. Young, and Torben Martinussen


Discussion

Isabel Fulcher, Ilya Shpitser, Vanessa Didelez, Kali Zhou, and Daniel O. Scharfstein


Rejoinder

Yen-Tsung Huang


Semiparametric partial common principal component analysis for covariance matrices

Bingkai Wang, Xi Luo, Yi Zhao, and Brian Caffo


Semiparametric models and inference for the effect of a treatment when the outcome is nonnegative with clumping at zero

Jing Cheng and Dylan S. Small


A marginal moment matching approach for fitting endemic-epidemic models to underreported disease surveillance counts

Johannes Bracher and Leonhard Held


Non-parametric cluster significance testing with reference to a unimodal null distribution

Erika S. Helgeson, David M. Vock, and Eric Bair


Nonparametric matrix response regression with application to brain imaging data analysis

Wei Hu, Tianyu Pan, Dehan Kong, and Weining Shen


Efficient nonparametric inference on the effects of stochastic interventions under two-phase sampling, with applications to vaccine efficacy trials

Nima S. Hejazi, Mark J. van der Laan, Holly E.Janes, Peter B. Gilbert, and David C. Benkeser


Net benefit index: assessing the influence of a biomarker for individualized treatment rules

Yiwang Zhou, Peter X.K. Song, and Haoda Fu


A class of proportional win-fractions regression models for composite outcomes

Lu Mao and Tuo Wang


Evaluating and improving a matched comparison of antidepressants and bone density

Ruoqi Yu


Modeling excess hazard with time-to-cure as a parameter

Olayidé Boussari, Laurent Bordes, Gaëlle Romain, Marc Colonna, Nadine Bossard, Laurent Remontet, and Valérie Jooste


A pairwise pseudo-likelihood approach for left-truncated and interval-censored data under the Cox model

Peijie Wang, Danning Li, and Jianguo Sun


Evaluating multiple surrogate markers with censored data

Layla Parast, Tianxi Cai, and Lu Tian


Modelling sparse longitudinal data on Riemannian manifolds

Xiongtao Dai, Zhenhua Lin, and Hans-Georg Mueller


A stacked approach for chained equations multiple imputation incorporating the substantive model

Lauren J. Beesley and Jeremy M. G. Taylor


Penalized Fieller’s confidence interval for the ratio of bivariate normal means

Peng Wang, Siqi Xu, Yixin Wang, Baolin Wu, Wing Kam Fung, Guimin Gao, Zhijiang Liang, and Nianjun Liu


Poisson PCA: Poisson measurement error corrected PCA, with application to microbiome data

Toby Kenney, Hong Gu, and Tianshu Huang


A random covariance model for bi-level graphical modeling with application to resting-state fMRI data

Lin Zhang, Andrew DiLernia, Karina Quevedo, Jazmin Camchong, Kelvin Lim, and Wei Pan


Histopathological imaging-based cancer heterogeneity analysis via penalized fusion with model averaging

Baihua He, Tingyan Zhong, Jian Huang, Yanyan Liu, Qingzhao Zhang, and Shuangge Ma


Brain connectivity alteration detection via matrix-variate differential network model

Jiadong Ji, Yong He, Lei Liu, and Lei Xie


Receiver operating characteristic curves and confidence bands for support vector machines

Daniel J. Luckett, Eric B. Laber, Samer S. El-Kamary, Cheng Fan, Ravi Jhaveri, Charles M. Perou, Fatma M. Shebl, and Michael R. Kororok


A Bayesian approach to restricted latent class models for scientifically-structured clustering of multivariate binary outcomes

Zhenke Wu, Livia Casciola-Rosen, Antony Rosen, and Scott L. Zeger


Using the “hidden” genome to improve classification of cancer types

Saptarshi Chakraborty, Colin B. Begg, and Ronglai Shen


Child mortality estimation incorporating summary birth history data

Katie Wilson and Jon Wakefield


Biometric Practice


DISCUSSION PAPER

Improving precision and power in randomized trials for COVID-19 treatments using covariate adjustment, for binary, ordinal, and time-to-event outcomes

David Benkeser, Ivan Diaz, Alex Luedtke, Jodi Segal, Daniel Scharfstein, and Michael Rosenblum


Discussion

Michael A. Proschan


Discussion

Min Zhang and Baqun Zhang


Discussion

Lisa M. LaVange


Rejoinder

David Benkeser, Ivan Diaz, Alex Luedtke, Jodi Segal, Daniel Scharfstein, and Michael Rosenblum


Book reviews


Replication and Evidence Factors in Observational Studies (Paul Rosenbaum)

Reviewed by Rajarshi Mukherjee


Matrix-Based Introduction to Multivariate Data Analysis, 2nd edition (Kohei Adachi)

Reviewed by Lin Liu


Biometry for Forestry and Environmental Data, with Examples in R (Lauri Mehtätalo and Juha Lappi)

Reviewed by Bianca N.I. Eskelson


Data Analysis with RStudio: An Easygoing Introduction (Franz Kronthaler and Silke Zöllner)

Reviewed by Mei-Hsien Lee


Data Science and Machine Learning: Mathematical and Statistical Methods (Dirk P. Kroese, Zdravko I. Botev, Thomas Taimre, and Radislav Vaisman)

Reviewed by Yin-Ju Lai and Chuhsing Kate Hsiao


Papers to appear in future issues of Biometrics


Robust methods to correct for measurement error when evaluating a surrogate marker

Layla Parast, Tanya P. Garcia, Ross L. Prentice, and Raymond J. Carroll


Simultaneous variable selection and estimation for joint models of longitudinal and failure time data with interval censoring

Fengting Yi, Niansheng Tang, and Jianguo Sun


A non-parametric Bayesian model for estimating spectral densities of resting-state EEG twin data

Brian Hart, Michele Guindani, Stephen Malone, and Mark Fiecas


New multivariate tests for assessing covariate balance in matched observational studies

Hao Chen and Dylan S. Small


Identifying individual predictive factors for treatment efficacy

Ariel Alonso, Wim Van der Elst, Lizet Sanchez, Patricia Luaces, and Geert Molenberghs


Analysis of clustered interval-censored data using a class of semiparametric partly linear frailty transformation models

Chun Yin Lee, Kin Yau Wong, K. F. Lam, and Jinfeng Xu


A closed max-t test for multiple comparisons of areas under the ROC curve

Paul Blanche, Jean-Francois Dartigues, and Jeremie Riou


Speeding up Monte Carlo simulations for the adaptive sum of powered score test with importance sampling

Yangqing Deng, Yinqiu He, Gongjun Xu, and Wei Pan


Statistical inference for association studies using electronic health records: handling both selection bias and outcome misclassification

Lauren J. Beesley and Bhramar Mukherjee


Joint calibrated estimation of inverse probability of treatment and censoring weights for marginal structural models

Sean Yiu and Li Su


Simultaneous spatial smoothing and outlier detection using penalized regression, with application to childhood obesity surveillance from electronic health records

Young-Geun Choi, Lawrence P. Hanrahan, Derek Norton, and Ying-Qi Zhao


Estimating the optimal individualized treatment rule from a cost-effectiveness perspective

Yizhe Xu, Tom H. Greene, Adam P. Bress, Brian C. Sauer, Brandon K. Bellows, Yue Zhang, William S. Weintraub, Andrew E. Moran, and Jincheng Shen


A latent capture history model for digital aerial surveys

D. L. Borchers, P. Nightingale, B. C. Stevenson, and R. M. Fewster


Non-linear mediation analysis with high-dimensional mediators whose causal structure is unknown

Wen Wei Loh, Beatrijs Moerkerke, Tom Loeys, and Stijn Vansteelandt


Power and sample size for observational studies of point exposure effects

Bonnie E. Shook-Sa and Michael G. Hudgens


Weight calibration to improve efficiency for estimating pure risks from the additive hazards model with the nested case-control design

Yei EunShin, Ruth M. Pfeiffer, Barry I. Graubard, and Mitchell H. Gail


Obtaining optimal cutoff values for tree classifiers using multiple biomarkers

Yuxin Zhu and Mei-Cheng Wang


Modelling group movement with behavior switching in continuous time

Mu Niu, Fay Frost, Jordan Milner, Anna Skarin, and Paul G. Blackwell


Semiparametric imputation using conditional Gaussian mixture models under item nonresponse

Danhyang Lee and Jae Kwang Kim


Two robust tools for inference about causal effects with invalid instruments

Hyunseung Kang, Youjin Lee, T. Tony Cai, and Dylan S. Small


Reader Reaction: Biased estimation with shared parameter models in the presence of competing dropout mechanisms

Edward F. Vonesh and Tom Greene


Rejoinder

Christos Thomadakis, Loukia Meligkotsidou, Nikos Pantazis, and Giota Touloumi


Restricted mean survival time as a function of restriction time

Yingchao Zhong and Douglas Earl Schaubel


Generalized multi-SNP mediation intersection-union test

Wujuan Zhong, Toni Darville, Xiaojing Zheng, Jason Fine, and Yun Li


Assuming independence in spatial latent variable models: Consequences and implications of misspecification

Francis Hui, Nicole A. Hill, and Alan Welsh


Causal Inference in high dimensions: A marriage between Bayesian modeling and good frequentist properties

Joseph Antonelli, Georgia Papadogeorgou, and Francesca Dominici


A spatial Bayesian latent factor model for image-on-image regression

Cui Guo, Jian Kang, and Timothy D. Johnson


Simultaneous confidence intervals for ranks with application to ranking institutions

Diaa Al Mohamad, Jelle Goeman, and Erik van Zwet


Bayesian group sequential enrichment designs based on adaptive regression of response and survival time on baseline biomarkers

Yeonhee Park, Suyu Liu, Peter Thall, and Ying Yuan


Synthesizing external aggregated information in the presence of population heterogeneity: A penalized empirical likelihood approach

Ying Sheng, Yifei Sun, Chiung-Yu Huang, and Mi-Ok Kim


A model for analysing clustered occurrence data

Wen-Han Hwang, Richard Huggins, and Jakub Stoklosa


Two-stage penalized regression screening to detect biomarker-treatment interactions in randomized clinical trials

Jixiong Wang, Ashish Patel, James Wason, and Paul Newcombe


Small-sample inference for cluster-based outcome-dependent sampling schemes in resource-limited settings: investigating low birthweight in Rwanda

Sara Sauer, Bethany Hedt-Gauthier, Claudia Rivera-Rodriguez, and Sebastien Haneuse


Bayesian dose-regimen assessment in early phase oncology incorporating pharmacokinetics and pharmacodynamics

Emma Gerard, Sarah Zohar, Hoai-Thu Thai, Christelle Lorenzato, Marie-Karelle Riviere, and Moreno Ursino


Gaussian graphical model-based heterogeneity analysis via penalized fusion

Mingyang Ren, Sanguo Zhang, Qingzhao Zhang, and Shuangge Ma


Joint model for survival and multivariate sparse functional data with application to a study of Alzheimer's disease

Cai Li, Luo Xiao, and Sheng Luo


Density estimation for circular data observed with errors

Marco Di Marzio, Stefania Fensore, Agnese Panzera, and Charles Taylor


Bayesian data fusion: probabilistic sensitivity analysis for unmeasured confounding using informative priors based on secondary data

Leah Comment, Brent Coull, Corwin M. Zigler, and Linda Valeri


Information-incorporated Gaussian graphical model for gene expression data

Huangdi Yi, Qingzhao Zhang, Cunjie Lin, and Shuangge Ma


Random effects models of lymph node metastases in breast cancer: quantifying the roles of covariates and screening using a continuous growth model

Gabriel Isheden, Kamila Czene, and Keith Humphreys


Pursuing sources of heterogeneity in modeling clustered population

Yan Li, Chun Yu, Yize Zhao, Weixin Yao, Robert H. Aseltine, and Kun Chen


Causal interaction trees: Finding subgroups with heterogeneous treatment effects in observational data

Jiabei Yang, Issa J. Dahabreh, and Jon A. Steingrimsson


A kernel regression model for panel count data with nonparametric covariate functions

Yang Wang and Zhangsheng Yu


EMBRACE: an EM-based bias reduction approach through Copas-model estimation for quantifying the evidence of selective publishing in network meta-analysis

Arielle K. Marks-Anglin, Chongliang Luo, Jin Piao, Mary Beth Connolly Gibbons, Christopher Schmid, Jing Ning, and Yong Chen


Bayesian spatial homogeneity pursuit for survival data with an application to the SEER respiratory cancer data

Lijiang Geng and Guanyu Hu


Geostatistical modeling of positive definite matrices: An application to diffusion tensor imaging

Zhou Lan, Brian Reich, Joseph Guinness, Dipankar Bandyopadhyay, Liangsuo Ma, and F. Gerard Moeller


The Tukey trend test: Multiplicity adjustment using multiple marginal models

Frank Schaarschmidt, Christian Ritz, and Ludwig Hothorn


Varying coefficient frailty models with applications in single molecular experiments

Ying Hung, Li-Hsiang Lin, and C. F. Jeff Wu


Identifying regions of inhomogeneities in spatial processes via an M-RA and mixture priors

Marco H. Benedetti, Veronica J. Berrocal, and Naveen N. Narisetty


Determination and estimation of optimal quarantine duration for infectious diseases with application to data analysis of COVID-19

Ruoyu Wang and Qihua Wang


Simultaneous estimation of cluster number and feature sparsity in high-dimensional cluster analysis

Yujia Li, Xiangrui Zeng, Chien-Wei Lin, and George C. Tseng


Recruitment prediction for multi-centre clinical trials based on a hierarchical Poisson-gamma model: asymptotic analysis and improved intervals

Rachael Mountain and Chris Sherlock


Semiparametric estimation of the non-mixture cure model with auxiliary survival information

Bo Han, Ingrid Van Keilegom, and Xiaoguang Wang


Global sensitivity analysis of randomized trials with non-monotone missing binary outcomes: application to studies of substance use disorders

Daniel O. Scharfstein, Jon Steingrimsson, Aidan McDermott, Chenguang Wang, Souvik Ray, Aimee Campbell, Edward Nunes, and Abigail Matthews


Regression-based negative control of homophily in dyadic peer effect analysis

Lan Liu and Eric Tchetgen Tchetgen


Non-parametric estimation of Spearman’s rank correlation with bivariate survival data

Svetlana Eden, Chun Li, and Bryan Shepherd


A Bayesian spatial model for imaging genetics

Yin Song, Shufei Ge, Jiguo Cao, Liangliang Wang, and Farouk Salim Nathoo


Spatial factor modeling: A Bayesian matrix-normal approach for misaligned data

Lu Zhang and Sudipto Banerjee


Cox regression model under dependent truncation

Lior Rennert and Sharon X. Xie


Sparse linear discriminant analysis for multi-view structured data

Sandra E. Safo, Eun Jeong Min, and Lillian Haine


Variance reduction in the inverse probability weighted estimators for the average treatment effect using the propensity score

J. G. (Jiangang) Liao and Charles Rohde


A generalized robust allele-based genetic association test

Lin Zhang and Lei Sun


Modeling dynamic correlation in zero-inflated bivariate count data with applications to single-cell RNA sequencing data

Zhen Yang and Yen-Yi Ho


Distributional independent component analysis for diverse neuroimaging modalities

Ben Wu, Subhadip Pal, Jian Kang, and Ying Guo


Discussion on "Distributional independent component analysis for diverse neuroimaging modalities" by Ben Wu, Subhadip Pal, Jian Kang, and Ying Guo

Heather Shappell and Sean L. Simpson


Discussion on "Distributional independent component analysis for diverse neuroimaging modalities" by Ben Wu, Subhadip Pal, Jian Kang, and Ying Guo

Amanda Mejia


Discussion on "Distributional independent component analysis for diverse neuroimaging modalities" by Ben Wu, Subhadip Pal, Jian Kang, and Ying Guo

Kan Keeratimahat and Thomas E. Nichols


Discussion on "Distributional independent component analysis for diverse neuroimaging modalities" by Ben Wu, Subhadip Pal, Jian Kang, and Ying Guo

Beatrijs Moerkerke and Ruth Seurinck


Rejoinder to "Distributional independent component analysis for diverse neuroimaging modalities"

Ben Wu, Subhadip Pal, Jian Kang, and Ying Guo


Inverse probability weighted estimators of vaccine effects accommodating partial interference and censoring

Sujatro Chakladar, Samuel P. Rosin, Michael G. Hudgens, M. Elizabeth Halloran, John D. Clemens, Mohammad Ali, and Michael E. Emch,


Integrative analysis of multiple case-control studies

Han Zhang, Lu Deng, William Wheeler, Jing Qin, and Kai Yu


On polygenic risk scores for complex traits prediction

Bingxin Zhao and Fei Zou


Restricted function-on-function linear regression model

Ruiyan Luo and Xin Qi


A transformation-free linear regression for compositional outcomes and predictors

Jacob Fiksel, Scott L. Zeger, and Abhirup Datta


Inferring UK COVID-19 fatal infection trajectories from daily mortality data: were infections already in decline before the UK lockdowns?

Simon N. Wood


Testing for association in multi-view network data

Lucy L. Gao, Daniela Witten, and Jacob Bien


Parameter inference for a stochastic kinetic model of expanded polyglutamine proteins

H. F. Fisher, R. J. Boys, C. S. Gillespie, C. J. Proctor, and A. Golightly


Multivariate survival analysis in big data: a divide-and-combine approach

Wei Wang, Shou-En Lu, Jerry Q. Cheng, Minge Xie, and John B. Kostis


Bayesian analysis of coupled cellular and nuclear trajectories for cell migration

Saptarshi Chakraborty, Tian Lan, Yiider Tseng, and Samuel W.K. Wong


A consistent version of distance covariance for right-censored survival data and its application in hypothesis testing

Dominic Edelmann, Thomas Welchowski, Axel Benner


Stratified Cox models with time-varying effects for national kidney transplant patients: A new block-wise steepest ascent method

Kevin He, Ji Zhu, Jian Kang, and Yi Li


Semiparametric analysis of clustered interval-censored survival data using Soft Bayesian Additive Regression Trees (SBART)

Piyali Basak, Antonio Ricardo Linero, Debajyoti Sinha, and Stuart R. Lipsitz


Optimization of sampling designs for pedigrees and association studies

Olivier David, Arnaud Le Rouzic, and Christine Dillmann


Feature screening with large scale and high dimensional survival data

Grace Yi, Wenqing He, and Raymond J. Carroll


Regression with interval-censored covariates: application to cross-sectional incidence estimation

Doug Morrison, Oliver Laeyendecker, and Ron Brookmeyer


Efficient detection and classification of epigenomic changes under multiple conditions

Pedro L. Baldoni, Naim U. Rashid, and Joseph G. Ibrahim


Quantifying direct and indirect effect for longitudinal mediator and survival outcome using joint modeling approach

Cheng Zheng and Lei Liu


Spatial+: a novel approach to spatial confounding

Emiko Dupont, Simon N. Wood, and Nicole H. Augustin


Discussion on "Spatial+: a novel approach to spatial confounding" by Emiko Dupont, Simon N. Wood, and Nicole H. Augustin

Brian J. Reich, Shu Yang, and Yawen Guan


Discussion on "Spatial+: a novel approach to spatial confounding" by Emiko Dupont, Simon N. Wood, and Nicole H. Augustin

Isa Marques and Thomas Kneib


Discussion on "Spatial+: a novel approach to spatial confounding" by Emiko Dupont, Simon N. Wood, and Nicole H. Augustin

Alexandra M. Schmidt


Discussion on "Spatial+: a novel approach to spatial confounding" by Emiko Dupont, Simon N. Wood, and Nicole H. Augustin

Georgia Papadogeorgou


Semiparametric estimation of structural nested mean models with irregularly spaced longitudinal observations

Shu Yang


Estimating vaccine efficacy over time after a randomized study is unblinded

Anastasios A. Tsiatis and Marie Davidian


Discussion on "Estimating vaccine efficacy over time after a randomized study is unblinded" by Anastasios A. Tsiatis and Marie Davidian

M. Elizabeth Halloran


Discussion on "Estimating vaccine efficacy over time after a randomized study is unblinded" by Anastasios A. Tsiatis and Marie Davidian

Holly Janes, Fei Gao, and Alex Luedtke


Discussion on "Estimating vaccine efficacy over time after a randomized study is unblinded" by Anastasios A. Tsiatis and Marie Davidian

Dean Follmann


Rejoinder to "Estimating Vaccine Efficacy Over Time After a Randomized Study is Unblinded"

Anastasios A. Tsiatis and Marie Davidian


Modeling semi-competing risks data as a longitudinal bivariate process

Daniel Nevo, Deborah Blacker, Eric B. Larson, and Sebastien Haneuse


Utilizing stability criteria in choosing feature selection methods yields reproducible results in microbiome data

Lingjing Jiang, Niina Haiminen, Anna-Paola Carrieri, Shi Huang, Yoshiki Vazquez-Baeza, Laxmi Parida, Ho-Cheol Kim, Austin D. Swafford, Rob Knight, and Loki Natarajan


Non-parametric estimation in an illness-death model with component-wise censoring

Anne Eaton, Yifei Sun, James Neaton, and Xianghua Luo


Addressing patient heterogeneity in disease predictive model development

Xu Gao, Weining Shen, Jing Ning, Ziding Feng, and Jianhua Hu


Non-homogeneous Markov chain for estimating the cumulative risk of multiple false positive screening tests

Marzieh Kadkhodaei Golmakani, Rebecca A. Hubbard, and Diana Miglioretti


Simulation-based estimators of analytically intractable causal effects

Antonio R. Linero


A semi-parametric model for between-subject attributes: applications to beta-diversity of microbiome data

J. Liu, X. Zhang, T. Chen, T. Wu, T. Lin, L. Jiang, S. Lang, L. Liu, L. Natarajan, J.X. Tu, T. Kosciolek, J. Morton, T. Nguyen, B. Schnabl, R. Knight, C. Feng, Y. Zhong, and X.M. Tu


Tensor envelope mixture model for simultaneous clustering and multiway dimension reduction

Kai Deng and Xin Zhang


Spatial correlation structures for detections of individuals in spatial capture-recapture models

Ben Courtney Stevenson, Rachel M. Fewster, and Koustubh Sharma


A multi-view model for relative and absolute microbial abundances

Brian D. Williamson, James P. Hughes, and Amy D. Willis


Sample size formula for general win ratio analysis

Lu Mao, KyungMann Kim, and Xinran Miao


A Bayesian nonparametric approach for inferring drug combination effects on mental health in people with HIV

Wei Jin, Yang Ni, Leah H. Rubin, Amanda B. Spence, and Yanxun Xu


WiSER: robust and scalable estimation and inference of within-subject variances from intensive longitudinal data

Christopher A. German, Janet S. Sinsheimer, Jin Zhou, and Hua Zhou


Group sequential testing for cluster randomization trials with time-to-event endpoint

Sin-Ho Jung and Jianghao Li


Bridging preference-based instrumental variable studies and cluster-randomized encouragement experiments: study design, noncompliance, and average cluster effect ratio

Bo Zhang, Siyu Heng, Emily J. MacKay, and Ting Ye


Estimating mean potential outcome under adaptive treatment length strategies in continuous time

Hao Sun, Ashkan Ertefaie, and Brent Johnson


Design-based properties of the nearest neighbour spatial interpolator and its bootstrap mean squared error estimator

Lorenzo Fattorini, Marzia Marcheselli, Caterina Pisani, and Luca Pratelli


Pool adjacent violators algorithm assisted learning with application on estimating optimal individualized treatment regimes

Baojiang Chen, Ao Yuan, and Jing Qin


Multivariate Bayesian clustering using covariate-informed components with application to boreal vegetation sensitivity

Henry R. Scharf, Ann Raiho, Sierra Pugh, Carl Roland, David Swanson, Sarah Stehn, and Mevin Hooten


Flexible use of Copula-type model for dose-finding in drug combination clinical trials

Koichi Hashizume, Jun Tshuchida, and Sozu Takashi,


Efficient odds ratio estimation under two-phase sampling using error-prone data from a multi-national HIV research cohort

Sarah C. Lotspeich, Bryan E. Shepherd, Gustavo G. C. Amorim, Pamela A. Shaw, and Ran Tao


Integration of survival data from multiple studies

Steffen Ventz, Rahul Mazumder, and Lorenzo Trippa


Joint modeling of zero-inflated longitudinal proportions and time-to-event data with application to a gut microbiome study

Jiyuan Hu, Chan Wang, Martin J. Blaser, and Huilin Li


A linear noise approximation for stochastic epidemic models fit to partially observed incidence counts

Jonathan Fintzi, Jon Wakefield, and Vladimir N. Minin


Another look at regression analysis using ranked set samples with application to an osteoporosis study

Nasrin Faraji, Mohammad Jafari Jozani, and Nader Nematollahi


Varying-coefficient regression analysis for pooled biomonitoring

Dewei Wang, Xichen Mou, and Yan Liu


Weak-instrument robust tests in two-sample summary-data Mendelian randomization

Sheng Wang and Hyunseung Kang


A semiparametric isotonic regression model for skewed distributions with application to DNA-RNA-protein analysis

Chenguang Wang, Ao Yuan, Leslie Cope, and Jing Qin


Sample size estimation for cancer randomized trials in the presence of heterogeneous populations

Derek Dinart, Carine Bellera, and Virginie Rondeau


Multidimensional molecular measurements-environment interaction analysis for disease outcomes

Yaqing Xu, Mengyun Wu, and Shuangge Ma


Reducing subspace models for large-scale covariance regression

Alexander M. Franks


On estimating optimal regime for treatment initiation time based on restricted mean residual lifetime

Xin Chen, Rui Song, Jiajia Zhang, Swann Arp Adams, Liuquan Sun, and Wenbin Lu


Analysis of local sensitivity to nonignorability with missing outcomes and predictors

Heng Chen and Daniel F. Heitjan


Binacox: automatic cut-point detection in high-dimensional Cox model with applications in genetics

Simon Bussy, Mokhtar Z. Alaya, Anne-Sophie Jannot, and Agathe Guilloux


Bivariate small area estimation for binary and Gaussian variables based on a conditionally specified model

Hao Sun, Emily Berg, and Zhengyuan Zhu


Bayesian adaptive trial design for a continuous biomarker with possibly non-Linear or non-monotone prognostic or predictive effects

Yusha Liu, John A. Kairalla, and Lindsay A. Renfro


Joint association and classification analysis of multi-view data

Yunfeng Zhang and Irina Gaynanova


Extracting brain disease-related connectome subgraphs by adaptive dense subgraph discovery

Qiong Wu, Xiaoqi Huang, Adam Culbreth, James Waltz, Elliot Hong, and Shuo Chen


Nonparametric estimation of the survival distribution under covariate-induced dependent truncation

Bella Vakulenko-Lagun, Jing Qian, Sy-Han Chiou, Nancy Wang, and Rebecca A. Betensky


Re-calibrating pure risk integrating individual data from two-phase studies with external summary statistics

Jiayin Zheng, Yingye Zheng, and Li Hsu


Simultaneous variable selection in regression analysis of multivariate interval-censored data

Liuquan Sun, Shuwei Li, Lianming Wang, Xinyuan Song, and Xuemei Sui


Sufficient dimension reduction for populations with structured heterogeneity

Jared D. Huling and Menggang Yu


Hierarchical cancer heterogeneity analysis based on histopathological imaging features

Mingyang Ren, Qingzhao Zhang, Sanguo Zhang, Tingyan Zhong, Jian Huang, and Shuangge Ma


Accounting for post-randomization variables in meta-analysis: A joint meta-regression approach

Qinshu Lian, Jing Zhang, James S. Hodges, Yong Chen, and Haitao Chu


Elastic priors to dynamically borrow information from historical data in clinical trials

Liyun Jiang, Lei Nie, and Ying Yuan


Simultaneous feature selection and outlier detection with optimality guarantees

Luca Insolia, Ana Kenney, Francesca Chiaromonte, and Giovanni Felici


Human disease clinical treatment network for the elderly: Analysis of the Medicare inpatient length of stay and readmission data

Hao Mei, Ruofan Jia, Guanzhong Qiao, Zhenqiu Lin, and Shuangge Ma


Accelerated failure time modeling via nonparametric mixtures

Byungtae Seo and Sangwook Kang


Latent group detection in functional partially linear regression models

Wu Wang, Ying Sun, and Huixia Judy Wang


Sensitivity analyses informed by tests for bias in observational studies

Paul R. Rosenbaum


SMIM: a unified framework of survival sensitivity analysis using multiple imputation and Martingale

Shu Yang, Yilong Zhang, Guanghan Frank Liu, and Qian Guan


Causal inference with outcomes truncated by death in multiarm studies

Shanshan Luo, Wei Li, and Yangbo He


Reader Reaction to "Outcome-adaptive lasso: variable selection for causal inference" by Shortreed and Ertefaie (2017)

Ismaila Balde, Yi Yang, and Genevieve Lefebvre


Estimation of separable direct and indirect effects in continuous time

Torben Martinussen and Mats Julius Stensrud


Modelling publication bias and p-hacking

Jonas Moss and Riccardo De Bin


Interim monitoring in sequential multiple assignment randomized trials

Liwen Wu, Junyao Wang, and Abdus S. Wahed


On restricted mean time in favor of treatment

Lu Mao


Bayesian multiple index models for environmental mixtures

Glen McGee, Ander Wilson, Thomas F. Webster, and Brent A. Coull


Spectra in Low-Rank Localized Layers (SpeLLL) for interpretable time-frequency analysis

Marie Tuft, Martica H. Hall, and Robert T. Krafty


Variable selection in nonlinear function-on-scalar regression

Rahul Ghosal and Arnab Maity


A matching procedure for sequential experiments that iteratively learns which covariates improve power

Adam Kapelner and Abba Krieger


Dynamic logistic state-space prediction model for clinical decision making

Jiakun Jiang, Wei Yang, Erin M. Schnellinger, Stephen E. Kimmel, and Wensheng Guo


Instrumental variable estimation of complier causal treatment effect with interval-censored data

Shuwei Li and Limin Peng


Evaluating the association between latent classes and competing risks outcomes with multi-phenotype data

Teng Fei, John Hanfelt, and Limin Peng


Jackknife model averaging for high-dimensional quantile regression

Miaomiao Wang, Xinyu Zhang, Alan T. K. Wan, Kang You, and Guohua Zou


Generalized case-control sampling under generalized linear models

Jacob M. Maronge, Ran Tao, Jonathan S. Schildcrout, and Paul J. Rathouz


CASANOVA: Permutation inference in factorial survival designs

Marc Ditzhaus, Jon Genuneit, Arnold Janssen, and Markus Pauly


Bayesian non-parametric quantile process regression and estimation of marginal quantile effects

Steven G. Xu and Brian J. Reich


Estimating perinatal critical windows of susceptibility to environmental mixtures via structured Bayesian regression tree pairs

Daniel Mork and Ander Wilson


Adaptive enrichment designs with a continuous biomarker

Nigel Stallard


Discussion on "Adaptive enrichment designs with a continuous biomarker" by Nigel Stallard


Rachael V. Phillips and Mark J. van der Laan



Discussion on "Adaptive enrichment designs with a continuous biomarker" by Nigel Stallard


James M. S. Wason



Discussion on "Adaptive enrichment designs with a continuous biomarker" by Nigel Stallard


Christopher Jennison



Discussion on "Adaptive enrichment designs with a continuous biomarker" by Nigel Stallard


Nancy Flournoy and Sergey Tarima



Discussion on "Adaptive enrichment designs with a continuous biomarker" by Nigel Stallard


Nancy Flournoy and Sergey Tarima


Logistic regression analysis of two-phase studies using generalized method of moments

Prosenjit Kundu and Nilanjan Chatterjee


Inference in response-adaptive clinical trials when the enrolled population varies over time

Massimiliano Russo, Steffen Ventz, Victoria Xin Wang, and Lorenzo Trippa


Improving efficiency of inference in clinical trials with external control data

Xinyu Li, Wang Miao, Fang Lu, and Xiao-Hua Zhou


A linear mixed model to estimate COVID-19-induced excess mortality

Johan Verbeeck, Christel Faes, Thomas Neyens, Niel Hens, Geert Verbeke, Patrick Deboosere, and Geert Molenberghs


A novel statistical test for treatment differences in clinical trials using a response adaptive forward looking Gittins Index Rule

Helen Yvette Barnett, Sofia S. Villar, Helena Geys, and Thomas Jaki


Integrating sample similarities into latent class analysis: A tree-structured shrinkage approach

Mengbing Li, Daniel E. Park, Maliha Aziz, Cindy M. Liu, Lance B. Price, and Zhenke Wu


An individual level infectious disease model in the presence of uncertainty from multiple, imperfect diagnostic tests

Caitlin Ward, Grant D. Brown, and Jacob J. Oleson


Non-iterative adjustment to regression estimators with population-based auxiliary information for semiparametric models

Fei Gao, and K. C. G. Chan


De-biased Lasso for generalized linear models with a diverging number of covariates

Lu Xia, Bin Nan, and Yi Li


Functional additive models for optimizing individualized treatment rules

Hyung Park, Eva Petkova, Thaddeus Tarpey, and R. Todd Ogden


A smoothed corrected score approach for proportional hazards model with misclassified discretized covariates induced by error-contaminated continuous time-dependent exposure

Xiao Song, Edward C. Chao, and Ching-Yun Wang


Sample size considerations for stepped wedge designs with subclusters

Kendra Davis-Plourde, Monica Taljaard, and Fan Li


A novel Bayesian functional spatial partitioning method with application to prostate cancer lesion detection using MRI

Maria Masotti, Lin Zhang, Ethan Leng, Greg J. Metzger, and Joseph S. Koopmeiners


Semiparametric additive time-varying coefficients model for longitudinal data with censored time origin

Yanqing Sun, Qiong Shou, Peter B. Gilbert, Fei Heng, and Xiyuan Qian


Covariate adjustment in continuous biomarker assessment

Ziyi Li, Yijian Huang, Dattatraya Patil, and Martin G. Sanda


Risk prediction with imperfect survival outcome information from electronic health records

Jue Hou, Stephanie F. Chan, Xuan Wang, and Tianxi Cai


Testing for heterogeneity in the utility of a surrogate marker

Layla Parast, Tianxi Cai, and Lu Tian


Selective prediction-set models with coverage rate guarantees

Jean Feng, Arjun Sondhi, Jessica Perry, and Noah Simon


Supervised two-dimensional functional principal component analysis with time-to-event outcomes and mammogram imaging data

Shu Jiang, Jiguo Cao, Bernard Rosner, and Graham A. Colditz


Estimation of the odds ratio in a proportional odds model with censored time-lagged outcome in a randomized clinical trial

Anastasios A. Tsiatis, Marie Davidian, and Shannon T. Holloway


Variable selection in regression-based estimation of dynamic treatment regimes

Zeyu Bian, Erica E.M. Moodie, Susan M. Shortreed, and Sahir Bhatnagar


Assessing intervention effects in a randomized trial within a social network

Shaina J. Alexandria, Michael G. Hudgens, and Allison E. Aiello


Improving trial generalizability using observational studies

Dasom Lee, Shu Yang, Lin Dong, Xiaofei Wang, Donglin Zeng, and Jianwen Cai


A formal causal interpretation of the case-crossover design

Zach Shahn, Miguel A. Hernan, and James M. Robins


Estimating cell type composition using isoform expression one gene at a time

Hillary M. Heiling, Douglas R. Wilson, Naim U. Rashid, Wei Sun, and Joseph G. Ibrahim


Design and analysis of two-phase studies with multivariate longitudinal data

Chiara Di Gravio, Ran Tao, and Jonathan S. Schildcrout


Ultra-high dimensional variable selection for doubly robust causal inference


Dingke Tang, Dehan Kong, Wenliang Pan, and Linbo Wang


Bayesian inference for stationary points in Gaussian process regression models for event-related potentials analysis


Cheng-Han Yu, Meng Li, Colin Noe, Simon Fischer-Baum, and Marina Vannucci


Inference for nonparanormal partial correlation via regularized rank-based nodewise regression


Haoyan Hu and Yumou Qiu


Neural networks for clustered and longitudinal data using mixed effects models


Francesca Mandel, Riddhi Pratim Ghosh, and Ian Barnett



Semiparametric count data regression for self-reported mental health


Daniel R. Kowal and Bohan Wu



A repeated measures approach to pooled and calibrated biomarker data


Abigail Sloan, Chao Cheng, Bernard Rosner, Regina G. Ziegler, Stephanie A. Smith-Warner, and Molin Wang



Bayesian nonparametric analysis of restricted mean survival time


Chenyang Zhang and Guosheng Yin



Generalized network structured models with mixed responses subject to measurement error and misclassification


Qihuang Zhang and Yun Grace Yi



Leveraging a surrogate outcome to improve inference on a partially missing target outcome


Zachary R. McCaw, Sheila M. Gaynor, Ryan Sun, and Xihong Lin



Screening methods for linear errors-in-variables models in high dimensions


Linh H. Nghiem, Francis K.C. Hui, Samuel Muller, and A.H. Welsh



Bayesian nonparametric analysis for the detection of spikes in noisy calcium imaging data


Laura D'Angelo, Antonio Canale, Zhaoxia Yu, and Michele Guindani



A joint fairness model with applications to risk predictions for under-represented populations


Hyungrok Do, Shinjini Nandi, Preston Putzel, Padhraic Smyth, and Judy Zhong